The game marked the return of Triano, the former Raptors coach and Canadian, who was named the Suns' interim head coach after Earl Watson was sacked just three games into the season.
The team announced after the game that Booker suffered a strained left adductor (groin injury). DeRozan matched his season high with eight assists. Upstart rookie OG Anunoby added 16 points on 4-of-5 shooting beyond the arc while C.J.
The Raptors, who have scored 100 or more points in 10 consecutive games, nearly reached triple digits in three quarters Tuesday.
The margin reached 19 before a Suns surge cut the lead to 10 on a 3-pointer by Jared Dudley with 8:44 to play.
Booker, who shook off a 2-for-11 start to score a season-high 46 points Monday in a win at Philadelphia, shot 0 for 7 in the first half Tuesday.
Lowry had three three-pointers as part of a 13-point performance in the first quarter, and the Raptors took a 17-point lead on a driving reverse layup by Norman Powell with 33 seconds left in the frame.
Alex Len added 14 points and seven rebounds, and Troy Daniels and Josh Jackson each contributed 13 points for the Suns.
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After that slow start, Booker made 15 of his last 21 shots to finish with 46 points in the Suns' 115-101 win over the Sixers.
While Embiid finished with 22 points, 12 rebounds and four blocks, Chandler made him work on both ends and frustrated the young superstar at times. Phoenix had seven turnovers in the first while the Raptors had none.
While the Sixers would get it close in the fourth, Booker decided he'd had enough with his team up 11 and a little over three minutes remaining.
Two free throws by DeRozan had the lead at 17 with 4:23 left in the third. Suns interim coach Jay Triano became the first Canadian to be an National Basketball Association head coach when he led the Raptors from 2008-2011.
The Raptors play their next four games on the road, starting Friday in Memphis.
Phoenix is off Wednesday before hosting Washington Thursday.