The warning was released this evening after 4pm and is valid until tomorrow, Friday 8 December, at 6pm.
Cavan, Monaghan, Donegal, Longford, Leitrim, Mayo and Sligo have all been issued with an orange warning from Met Éireann, the second most severe of the warning systems for conditions with the capacity to "impact significantly" on people in affected areas.
Saturday is expected to be a mostly dry but very cold day with varying cloud and sunny spells.
A Status Yellow snow and ice warning is also in place for the remainder of the country, where accumulations of up to 3cm are expected.
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Accumulations of up to three centimetres are possible in parts while icy conditions are likely on the roads.
"Snow showers will occur this evening [Thursday], tonight and during Friday", read the warning on the official Met Éireann website.
Rain will spread northeast across the country on Saturday night.
Sunday is set to bring more outbreaks of sleet and snow over Ulster, most other places will be dry. Temperatures will be low and it will stay cold for most of next week. Scattered wintry showers also - mainly near coasts. High-sided vehicles and motorcyclists are particularly vulnerable to strong winds. Widespread frost early and late.