The game was tied when he found Garrett Celek on a 6-yard touchdown pass with about two minutes left in the third quarter to make it 23-16. He was replaced by TJ Yates after that. Yates engineered consecutive scoring drives upon entering the game, capping both with touchdown passes to receiver DeAndre Hopkins.
Savage was allowed to go back into the game, but was then taken out of the game and went to the locker room to be evaluated. After the hit, you can see Savage struggling to gather himself, nearly twitching on the ground. He threw two incompletions on that drive, and Houston's team doctor approached him after he returned to the sideline after that possession.
Savage was later pulled from the game, although he had to be restrained by personnel on the sideline as he attempted to return.
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Yates, who hadn't appeared in a game since November 16, 2015, was signed last month after Deshaun Watson went out with a knee injury. Garoppolo finished the game with 334 yards, one touchdown and one interception. It was his first career 300-yard passing game. He ripped off a 31-yard run before halftime that helped the 49ers get into field-goal range.
Hopkins finished with 11 receptions for 151 yards and two scores for the Texans (4-9), but his fumble in the fourth quarter resulted in the fourth Gould field goal.