The 54-year-old singer's post showed two images: One of Winfrey kissing the now-disgraced Hollywood mogul on the cheek with the words: "When you have been part of the problem for decades but suddenly they all think you are the solution".
Furthermore, the unapologetic and unconcerned tone struck in this meme stands in stark contrast to the comments that we know Winfrey actually made about the accusation levied at Weinstein.
In a post on his Instagram page, Seal shared a message for Oprah after her speech at the Golden Globes sparked rumors that she may run for president. "What I reposted was commentary on the hypocritical and the double standard nature and behavior of Hollywood".
She wrote, "I've been processing the accounts of Harvey Weinstein's disgusting behaviour and haven't been able to find the words to articulate the magnitude of the situation", before sharing a quote from filmmaker James Schamus.
At the Golden Globes, where she accepted the Cecil B. DeMille award, Winfrey proclaimed, "I want all the girls watching to know a new day is on the horizon".
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It was also reported in October that Oprah had privately lent her support to Weinstein. "Don't try and use me as a pawn against Oprah, or any of your political games", he added.
In fact, Model Chrissy Teigen came to Winfrey's defense and hit the singer with the best response.
Just saw @Oprah's empowering & inspiring speech at last night's #GoldenGlobes.
Seal's denouncement of Oprah comes as actress Kadian Noble alleges Weinstein used Winfrey to help lure her to his hotel room in France, where he allegedly assaulted her. Weinstein has denied these claims. The singer was married to Heidi Klum, who has herself been linked with Weinstein, as he served as the producer on her long-running reality show Project Runway. "Their time is up", Winfrey said.
On Wednesday, Family Guy creator Seth MacFarlane also questioned Winfrey's presidential ambitions, writing that a Trump-Winfrey matchup in 2020 would be "troublingly dystopian". "I think he'll be going on the floor".