One of their biggest obstacles to doing so comes on Sunday, as they travel to Anfield to take on Liverpool.
More importantly for City, they have won 94 per cent of the matches Sterling has scored in this season. That formation will be mirrored by Liverpool in this clash, the side's first since Philippe Coutinho completed his move to Barcelona.
I don't think Liverpool will be the first English team to beat Guardiola's charges this season - but given City's poor record at Anfield, I can't see them winning either.
Accompanied by a picture of the two players in Liverpool shirts with arms around each other, the message said: "Liverpool is no longer the same without the magical bro, I wish the infinite success for you, that you enjoy life".
Sturridge has not been involved in a game since the Champions League victory over Spartak Moscow on December 6 having suffered with illness and injury.
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In the receiving end, Keelan Cole posted 715 yards and three touchdowns while Marqise lee added 702 yards and three touchdowns. Better yet, how many defenders will they task with covering him on a given play? We didn't necessarily stick to our game plan.
Goals, goals and more goals are promised at Anfield on Sunday as the Premier League's top two scorers lock horns, with Liverpool hosting Manchester City in a titanic top-flight tussle.
While City have been irresistible at times this season, this is a strong Liverpool side - strengthened by the addition of Virgil van Dijk in defence.
Disappointingly for Sterling, he has yet to feature in a City team to defeat Liverpool in the league and over 90 minutes.
"We did very well to get him back following his loan here last season".