SC coach Frank Martin announced Holden's decision a short time before tip-off.
Auburn was down 45-23 at the time of the injury, and trailed by 20 or so for much of the first half.
Anfernee McLemore, who came into the weekend leading the SEC in blocked shots, suffered a devastating dislocated ankle on a rebound attempt with 11 minutes and 26 seconds left in the first half. Frank Booker scored 19 points, and SC built a 26-point lead before holding on to defeat No. 10 Auburn 84-75, ending the Gamecocks' six-game losing streak. McLemore is averaging 7.7 points and 5.3 rebounds per game. He landed awkwardly on his left ankle and appeared to dislocate it, a similar injury to what happened to the Celtics' Gordon Hayward in the opening game of the National Basketball Association season.
McLemore has started 21 of 27 games for the 10th-ranked Tigers this season.
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After the dominant performance on Day 1, Yun would need to falter badly over his final two runs to lose gold , and even more so to fall out of medal position.
Mustapha Heron led four Auburn players in double figures with 16 points, but 10 of those came from the foul line as he was just 3-for-12 from the field. The Tigers actually rebounded to get back in the game by the end.
Already facing a lack of depth in the post, Auburn will be short another key option as it looks to win the program's first SEC title since 1999. Jared Harper added 13 points, Chuma Okeke 11 and Bryce Brown 10 for a team that shot just 31.7 percent from the field for the game.
Saturday's loss certainly wasn't the first time Auburn was down double digits at halftime but South Carolina's 26-point lead right before that Heron dunk eclipsed its biggest 2017-18 deficit by almost ten points. Tip-off is scheduled for 7:30 p.m. CT on SEC Network.