Sleep deprivation linked to Alzheimer's disease, study suggests

Just one night of poor sleep can significantly increase levels of a toxic brain substance linked to Alzheimer's disease a study has found

Sleep deprivation linked to Alzheimer's disease, study suggests

Researchers don't know if higher levels of beta-amyloid showed up because sleep deprivation stopped the brain's routine cleaning process, or because the brain produced more of this protein as a result of being awake for so long.

Poor sleeping patterns may be linked to increased risk of Alzheimer's disease, a preliminary study by a group of researchers in the USA suggests.

The study, led by Dr Ehsan Shokri-Kojori, was published on Monday in the journal, the Proceedings of the National Academy of Sciences. Sure enough, people who got less sleep had slightly higher baseline levels of beta-amyloid, although it's impossible to say if this is due to their sleep habits specifically. The latest findings also showed that while sleeping, the neurons get shrunk by size and make spaces within the sets of cells to permit the waste materials to be removed from the brain.

The results: Nineteen out of 20 participants, whose ages ranged from 22 to 72, had higher beta-amyloid in their brains after their night of exhaustion compared to their well-rested baselines.

Beta-amyloid is linked to Alzheimer's, but is it a cause or effect of the disorder?

ACC announces the venues for Asia Cup and Emerging Nations tournament
Though the problem has been solved now and it is likely that the Men in Blue might play all their matches in the island nation. The Asia Cup has been marred by strained Indo-Pak relations since its inception when the UAE hosted it in 1984.

Nomura Boosts Alexion Pharmaceuticals (NASDAQ:ALXN) Price Target to $156.00
It turned negative, as 65 investors sold ALXN shares while 171 reduced holdings. 22 funds opened positions while 44 raised stakes. Proshare Advsr Ltd Liability Corporation has invested 0.22% in Alexion Pharmaceuticals , Inc. (NYSE:HP) or 300,721 shares.

Virgil van Dijk excited by opportunity to achieve something special
Guardiola said his side will need to produce "the flawless game" but Klopp is wary of the danger in even an imperfect performance. The last time that Liverpool won the competition was in 2005 after coming back from 3-0 down against the same opposition.

For one of the nights, the participants were allowed a restful period of sleep, but they were deprived sleep on the other night.

"The Australian sea lion experiences regular (about weekly) episodes of two to three days of complete sleep deprivation foraging in the sea for fish and then recovers lost sleep with three to four days of sleep and relaxation on the beach", says Lack. Cognitive outcomes were measured by the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) and the Clinical Dementia Rating Scale Sum of Boxes (CDR-sb).

Scientists believe that insomnia is one of the causes of Alzheimer's disease. Insomniacs accumulates an excessive amount of beta-amyloid in the brain.

The hippocampus plays a key role in memory while the thalamus acts as a relay centre for motor and sensory nerve signals. It is not clear yet whether disrupted sleep is just a symptom of the condition, or if it contributes to it. Good sleep is fundamental to proper brain function, but whether sleep deprivation, or disruption, plays a major role in the onset of dementia is still yet to be proven.

Latest News