Speaking after the win over Tottenham, Guardiola admitted winning the title in England would be one of the greatest achievements of his glittering career.
The City manager's decision to forego the match looked justified considering West Brom's terrible form, although Jake Livermore's early attempt was a warning shot that undercooked United failed to heed.
A number of stars are expected to be axed, including Smalling, Luke Shaw, Phil Jones, Matteo Darmian and Daley Blind. Both full-backs will need to be more proactive in their attacking play down the wings.
"In the first half I felt I had to bring one player with more dynamic, more of a runner, touch the ball in spaces, I had to make a decision of one midfield player, then after that I wanted more width and Paul had a yellow card and before the substitute he had a situtation where you never know with referees".
Manchester United signed Alexis Sanchez in a swap deal from Arsenal in the January transfer window.
Manchester United have 71 points, which is already the most the Red Devils have managed across a single season since Sir Alex Ferguson retired.
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Ultimately, Rodriguez was the hero for West Brom - and City. Winning titles in every league is important, with Barcelona was special.
"In the Premier League, I started at 19, so I knew that I will be one of those guys that's going to reach 100", he said.
"We've won the league for you, Man City, Man City", West Brom's fans chanted after the final whistle.
Before Lukaku was a star, he had a season-long loan spell with West Brom in 2012-13, which is when he catapulted to fame after a brilliant campaign that ended with him netting 17 goals including a hat-trick for the Baggies in a 5-5 draw against Manchester United, which was Sir Alex Ferguson's last fixture in charge. I just hope they don't go down and that they can learn from the mistakes that they made in the pre-season or whatever.
"You can't take them for granted - I've been lucky to win three but there have been so many I've missed as well", said Kompany.
"They won because they were the best team, they lost only a few points. We did not deserve to lose, we gave them opportunity to win the match".