State-run news agency SANA reported air defenses had shot down some of the missiles targeting the base.
Syria's air defenses shot down missiles targeting Shayrat air base in Homs province early Tuesday, state media reported, as a Hezbollah media arm said missiles targeting Dumayr base near Damascus were also intercepted.
Shayrat was hit past year by USA cruise missiles, launched in response to a chemical attack that killed at least 70 people in the rebel-held town of Khan Sheikhoun.
A top Russian chemical weapons protection expert, Igor Kirillov said experts from Organization for the Prohibition of Chemical Weapons are set to visit Douma tomorrow.
The news agency did not give further details and it was unclear who was behind the attack, which Syrian state television branded as an "aggression".
The decision comes two days after France took part in US-led air strikes on suspected chemical sites in Damascus following an alleged chemical attack in the Ghouta town of Douma. Social media reports are pointing the finger at Israel for the strikes.
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In Washington, Pentagon spokeswoman Heather Babb said: "There are no USA or coalition operations in that area".
The Syrian military believes Israeli warplanes were responsible..
"We don't comment on such reports", Reuters quoted a spokesman for the Israeli military as saying.
Israel's main concern in Syria is the growing influence of Iran, which it says supplies weapons to Hezbollah from inside the country.
That attack killed four Iranian military personnel - but Israel did not confirm or deny involvement.