I am just focused on what I am doing today. The victor plays Federer or Anderson. But the 26-year-old underdog isn't ruling out an epic upset against Williams.
Asked if he expected more from an opponent in the world's top 30, Federer said: "I think it's a tough matchup for him maybe against me".
Anderson added that Federer, who won his first Wimbledon title in 2003, is the flawless role model for the sport - and for those players in the chasing pack.
That won't happen here, at least not this year, for Tsitsipas or Shapovalov.
Bertens and Pliskova had reached the fourth round at Wimbledon for the first time.
And though his Wimbledon debut ended there Monday, when he ran into the big serve and arrhythmic game of the 6-foot-10 John Isner, Tsitsipas said he was pleased to have achieved his goal.
Kerber was the runner-up at the All England Club in 2016, while 14th-seeded Kasatkina is in the last eight for the first time.
Djokovic made light work of Tennys Sandren in the first round, before dropping just six games once more en route to beating Horacio Zeballos in the second.
It was tennis for the gluttonous: a feast.
He eventually finished off world number 53 Simon in the match's third tiebreak to move into his second Wimbledon quarter-final where twice champion Nadal is waiting.
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Serena Williams has lost a set for the first time at this Wimbledon.
Anderson, beaten by Murray in his only match on Centre Court, has lost all four career meetings with Federer who has won 32 consecutive sets at Wimbledon. "The only different thing", he said, "is that it's Federer in front of me".
He'd never even been past the third round at the grass-court Grand Slam until this year.
Leading 2-0 in the first set, Mannarino's fault serve was defended by Federer in an nearly "cricket-like" fashion.
What lies ahead will now test Nadal to the fullest, though.
But the 23-time major winner's blistering form and a series of shock results have paved the way for another Williams coronation at Wimbledon.
"Well, it's going to happen anyway, if I'm going in the final or not, the Wimbledon final will take place, and so will the World Cup final", Federer said in a seemingly tongue-in-cheek response.
Nadal demolished the giant Argentine for the loss of just seven games in the French Open semi-finals last month.