Williams had been favoured to draw level on Saturday but, despite turning 37 in September and suffering only her third defeat in 10 finals at The All England Club, the former world No.1 maintains more majors are still to come.
Meanwhile, Kerber, who lost against Williams two years ago, said she was delighted with securing her first Wimbledon title.
USA tennis star Serena Williams lost at Wimbledon during her comeback season after having a baby.
Kerber endured a hard 2017 after her most successful campaign the previous year and went without a tournament win for 12 months.
If Williams does earn one more, it'll tie her with Margaret Court for the all-time record of 24.
Williams was bedridden for six weeks after suffering life-threatening complications following the birth of her first child just 10 months ago, but defied the odds to enjoy a dream run to another final at the All England Club.
"Days after our baby girl was born, I kissed my wife goodbye before surgery and neither of us knew if she would be coming back, the Reddit co-founder and venture capitalist wrote. I'm literally just getting started so I'll look forward to it".
"You're such an inspiration for everybody", Kerber said to Williams during her post-match interview Saturday.
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"It was a great opportunity for me", she added.
She said: "I think without 2017 I couldn't win this tournament". I have not much more inside me. I learned so many things about myself.
"I'm just me. That's all I can be", Williams said about playing as a mother. She broke Williams' serve thrice in the first set and never looked back from thereon.
Kerber should in theory pose a much sterner test in what is a repeat of the 2016 final, which Williams won in straight sets. She was the favorite every time she entered a tournament. After the final, Williams took to Twitter to express her appreciation for her fans with a shout-out to all moms.
"These two weeks were so mental for me", she said.
Serena Williams returned to world's top 30 in the WTA rankings released on Monday after finishing as Wimbledon runner-up. "And to hold this trophy now, it is something that I can't describe".
In a role reversal from her wedding - at which Williams was a guest in May - Meghan Markle, the Duchess of Sussex, watched her friend alongside sister-in-law Kate Middleton, the Duchess of Cambridge, from the royal box.