On reporter's inquiry about Mendy, who is now recovering from a knee ligament injury that has sidelined him since November, Guardiola laughed at the report and even queried a club press officer to see if he had any ideas.
'He said he was going to Paris for one day, but Hong Kong?
Guardiola confirmed the French defender was in Barcelona on Thursday after treatment on a knee injury, which has been forced to miss the last three months of the season.
That was the question on everyone's lips at Manchester City on Friday.
But he later uploaded a video in a auto with the location set as Hong Kong International Airport, something which prompted Guardiola to swear on live television after he was questioned about Mendy's whereabouts in a pre-match press conference.
Asked why Mendy was in Hong Kong, Guardiola said: "Wow".
First, the Spaniard turned up wearing a striking top with multi-coloured stripes that may have had viewers watching his pre-match press conference on Sky Sports adjusting their sets. I have to understand Instagram. F***, he's a lucky guy.
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When asked about Mendy's post, Guardiola said: "Wow, I didn't know".
Guardiola's comical reaction to Mendy's whereabouts soon vent viral with the hashtag #WhereIsMendy trending on social media.
"I have a lot of respect".
"I had tickets to go but the Premier League chose to put the game at Everton then".
"I know the fans love it, but the manager is the chief of the team, so when he says something I have to listen to him", he added. They have, however, played a game more than Liverpool, who they replaced at the summit.
Liverpool were three points ahead of City before Guardiola's side defeated Everton 2-0 earlier this week.