According to Yahoo, the Pistons are concerned Griffin's knee will swell if he returns during this series, as it did when he came back after a three-game absence in early April.
There was hope that he'd be ready to go on Sunday, but prior to the game coach Dwane Casey made it known that, while still day-to-day, Griffin would not play in Game 1.
Pistons forward Blake Griffin averaged 24.5 points in 75 games during the regular season.
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"Griffin will be listed as day to day for the remainder of the series, with a league source calling it a "slim chance" he plays this weekend", Goodwill reported. It is unclear if he will require any sort of procedure in the off-season.
Budenholzer led the Bucks to 60 victories and the league's best record in his first season with Milwaukee.
Griffin has been the catalyst for the Pistons making the playoffs for only the second time in the last decade, and he's stayed largely healthy until this injury. The others were Brooklyn's Kenny Atkinson, Denver's Michael Malone, Indiana's Nate McMillan, San Antonio's Gregg Popovich, the Los Angeles Clippers' Doc Rivers, Utah's Quin Snyder and Portland's Terry Stotts.